Global NeuroSurg 1 (GNS-I Study)

Determining the Global Outcomes of Traumatic Brain Injury in Low-, Middle- and High-Income Countries: A Multi-center, International, Prospective Cohort Study

GNS-I study summary

Background

Every year, there are about sixty-nine million new cases of Traumatic Brain Injury (TBI) worldwide. However, there are wide variations in the management of TBI across low-, middle-, and high-income countries which affect TBI outcomes worldwide.

Study Design

GNS-I study is a multicenter, international, prospective cohort study that will start on the 1st of June 2019 to the 31st of March 2021 (last patient out).  The follow-up duration for each patient is 90 days.

Eligibility

The study will be conducted in self-selected registered centers worldwide. Any hospital receiving and managing TBI patients is eligible to participate in Global Neurosurg-1; There is no minimum patient number percenter; all consecutive cases must be included.

Study Duration and Team Members

Within the period from June 1, 2019, to December 31, 2020, each team (three people) selects a two-week period. Multiple teams in the same center can participate as long as they will collect data in different 2-week periods. Therefore, the maximum number of the team percenter is 18 teams (up to 54 collaborators).

Eligibility Criteria for patients

All TBI cases presenting at the study centers are eligible for inclusion in the study irrespective of their age and gender.

Data collection

We will collect anonymous data on patient demographics, TBI etiology and severity, clinical and surgical management, and the mortality rates at different time points. All data will be submitted to the secure RedCap system of the Brain Institute at Oregon Health and Science University, USA.

Ethical approvals

Study ethical approval will be acquired from all participating centers. All collected data will be kept confidential and will be used only for this study